### Standard 2c Preknowledge

*2c) Students know how random chromosome segregation explains the probability that a particular allele will be in a gamete.*

**CALIFORNIA FRAMEWORKS SUMMARY:**

The steps in meiosis involve random chromosome segregation, a process that accounts for the probability that a particular allele will be packaged in any given gamete. This process allows for genetic predictions based on laws of probability that pertain to genetic sortings. Students can create a genetic chart and mark alternate traits on chromosomes, one expression coming from the mother and another expression coming from the father. Students can be shown that partitions of the chromosomes are controlled by chance (are random) and that separation (segregation) of chromosomes during * karyokinesis* (division of the nucleus) leads to the random sequestering of different combinations of chromosomes.